Lecture

Gene Regulation II

This module builds upon Gene Regulation I, diving deeper into complex regulatory networks. Topics include:

  • Post-transcriptional regulation
  • The role of small RNAs in gene regulation
  • Feedback mechanisms in gene networks
  • Experimental approaches to studying gene regulation

Students will analyze case studies showcasing the significance of gene regulation in various biological contexts.


Course Lectures
  • This module introduces students to the fundamental concepts of biology and its applications. Key topics include:

    • The structure and function of biological macromolecules.
    • Cell structure and function, including cellular metabolism.
    • The basics of genetic information flow and expression.

    Students will engage with real-world applications of biological principles, enhancing their understanding of various biological systems.

  • Biochemistry I
    Graham Walker

    In Biochemistry I, students will delve into the chemistry of life, focusing on the molecular building blocks of biological systems. The module will cover:

    • Structure and function of proteins, carbohydrates, lipids, and nucleic acids.
    • Enzyme kinetics and the principles of metabolism.
    • How biochemical processes relate to cellular functions.

    This foundational knowledge will prepare students for advanced topics in biochemistry and molecular biology.

  • Biochemistry II
    Graham Walker

    Biochemistry II builds on the principles established in the first module, emphasizing metabolic pathways and regulation. Key areas of focus include:

    • Detailed examination of metabolic pathways, including glycolysis and the citric acid cycle.
    • Regulatory mechanisms controlling metabolic processes.
    • Integration of metabolism in different physiological states.

    Students will engage in case studies that highlight the relevance of biochemistry in health and disease.

  • Biochemistry III
    Graham Walker

    Biochemistry III focuses on the complex interactions and functions of biomolecules in living organisms. The module will cover:

    • Advanced protein structure and function.
    • Protein-protein interactions and enzymatic mechanisms.
    • Biochemical signaling pathways and their implications in cellular communication.

    This knowledge will assist students in understanding how biochemical processes underlie physiological responses.

  • Biochemistry IV
    Graham Walker

    In Biochemistry IV, students will explore more specialized topics, including:

    • Cellular bioenergetics and thermodynamics of biological systems.
    • The role of membranes in transport and communication.
    • Signal transduction pathways and their biological roles.

    This module combines theoretical knowledge with practical applications, preparing students for laboratory work.

  • Biochemistry V
    Graham Walker

    Biochemistry V emphasizes the biological relevance of macromolecules through systematic study, including:

    • Structural biology techniques.
    • Biophysical methods for studying macromolecules.
    • Applications of biochemistry in biotechnology and medicine.

    Students will develop skills necessary for laboratory-based research and practical applications.

  • Biochemistry VI
    Graham Walker

    Biochemistry VI concludes the series by integrating previous knowledge and focusing on current research in biochemistry. Topics include:

    • Recent advancements in biochemical research.
    • Case studies highlighting biochemistry's impact on health and disease.
    • Discussion on ethical implications of biochemistry in modern science.

    This module encourages critical thinking and prepares students for future research endeavors.

  • Molecular Biology II introduces the process of science and the methodologies used in biological research. In this module, students will learn about:

    • Experimental design and hypothesis testing.
    • Data analysis and interpretation.
    • Research ethics and responsible conduct in science.

    The module emphasizes hands-on experience with laboratory techniques and scientific communication.

  • Molecular Biology I
    Graham Walker

    Molecular Biology I serves as the foundation for understanding the molecular mechanisms of gene expression and regulation. Topics include:

    • The structure and function of DNA and RNA.
    • Transcription, translation, and post-translational modifications.
    • Gene regulation and epigenetic mechanisms.

    This module provides essential knowledge for students pursuing advanced studies in genetics and molecular biology.

  • Molecular Biology II, Process of Science - 2 expands on the concepts introduced in the previous module, focusing on advanced topics such as:

    • Techniques for studying gene function and regulation.
    • Applications of molecular biology in biotechnology.
    • Current trends in molecular research.

    This module prepares students for laboratory work and encourages them to engage with ongoing scientific discussions.

  • Molecular Biology III
    Graham Walker

    This module delves into the intricate processes of molecular biology, highlighting the mechanisms of gene expression and regulation. Students will explore:

    • The structural components of nucleic acids
    • The processes of transcription and translation
    • Methods for analyzing gene expression
    • Insights into molecular genetics techniques

    Through lectures and discussions, participants will gain a comprehensive understanding of how molecular interactions drive biological functions.

  • Molecular Biology IV
    Graham Walker

    This module continues exploring advanced molecular biology topics, focusing on the latest research and methodologies. Key areas include:

    • Gene editing technologies, such as CRISPR
    • Applications of molecular biology in medicine
    • The role of bioinformatics in gene analysis
    • Current trends in genetic research

    Students will engage with case studies that illustrate the impact of molecular biology on health and disease.

  • This continuation of Molecular Biology IV emphasizes gene regulation mechanisms. The module covers:

    • Key regulatory elements that control gene expression
    • Factors influencing transcriptional regulation
    • Epigenetic modifications and their roles
    • Technologies used to study gene regulation

    Through experimental design and analysis, students will learn how gene regulation affects cellular functions and organismal development.

  • Gene Regulation II
    Graham Walker

    This module builds upon Gene Regulation I, diving deeper into complex regulatory networks. Topics include:

    • Post-transcriptional regulation
    • The role of small RNAs in gene regulation
    • Feedback mechanisms in gene networks
    • Experimental approaches to studying gene regulation

    Students will analyze case studies showcasing the significance of gene regulation in various biological contexts.

  • Bacterial Genetics
    Graham Walker

    This module introduces bacterial genetics, emphasizing the unique features of prokaryotic systems. Key learning points include:

    • The structure and function of bacterial genomes
    • Mechanisms of genetic exchange among bacteria
    • Application of genetic tools in microbiology
    • The role of bacteria in ecosystems

    Students will engage in discussions around antibiotic resistance and its implications for public health.

  • The Biosphere
    Penny Chisholm

    This module explores the biosphere and its intricate connections. Students will learn about:

    • The definition and components of the biosphere
    • Interactions between living organisms and their environments
    • Biogeochemical cycles and their significance
    • The impact of human activity on the biosphere

    Discussions will include sustainability and conservation efforts to protect biodiversity.

  • This module emphasizes the processes of carbon and energy metabolism. Key topics include:

    • Photosynthesis and its role in energy capture
    • Cellular respiration pathways
    • Microbial contributions to carbon cycling
    • The interplay between energy flow and ecosystem dynamics

    Students will engage in lab activities to understand metabolic pathways and their ecological significance.

  • This module examines productivity and food webs, emphasizing ecosystem structure and function. Key points include:

    • Primary productivity and its measurement
    • The role of producers, consumers, and decomposers
    • Food web dynamics and energy transfer
    • Human impacts on food web structure

    Real-world examples will help students understand the complexity of ecological interactions.

  • This module explores the regulation of productivity in ecosystems, focusing on limiting factors and their effects. Key topics include:

    • Factors that limit primary productivity
    • Role of nutrients and light in ecosystem health
    • Human influences on nutrient cycles
    • Strategies for managing productivity in natural and agricultural systems

    Students will evaluate case studies that demonstrate the balance between ecosystem health and human resource use.

  • This final module addresses limiting factors and biogeochemical cycles, emphasizing the connections between ecological processes. Topics include:

    • Essential nutrients and their cycles
    • Limiting factors that affect ecosystem functioning
    • The interrelationship between biogeochemical cycles
    • Impacts of climate change on nutrient cycles

    Through analysis of current research, students will understand the importance of maintaining ecosystem balance.

  • Mendelian Genetics
    Graham Walker

    Mendelian Genetics forms the foundation of understanding inheritance patterns. This module explores Gregor Mendel's principles, including the law of segregation and independent assortment. Students will delve into how these principles apply to modern genetics and their significance in predicting genetic outcomes. Topics include monohybrid and dihybrid crosses, as well as the use of Punnett squares. Practical examples and exercises will enhance comprehension of genetic ratios and phenotypic expressions.

  • Mitosis and Meiosis
    Graham Walker

    This module focuses on the processes of mitosis and meiosis, essential for cell division and reproduction. Students will examine each phase of mitosis, from prophase to telophase, and understand how it leads to identical daughter cells. In contrast, meiosis will be discussed in terms of reducing the chromosome number by half, crucial for sexual reproduction. The module provides insights into the significance of these processes in growth, development, and genetic diversity.

  • Diploid Genetics
    Graham Walker

    Diploid Genetics examines the genetic composition of diploid organisms, which possess two sets of chromosomes. The module covers topics like allele interactions, dominance, recessiveness, and epistasis. Through real-world examples, students learn to analyze genetic traits and predict outcomes using tools like pedigrees and probability matrices. This knowledge is key to understanding genetic disorders and breeding strategies in plants and animals.

  • Recombinant DNA I
    Graham Walker

    Recombinant DNA I introduces students to the techniques and applications of recombinant DNA technology. This module covers the basics of gene cloning, vector selection, and insertion of genetic material into host cells. Students will learn about the tools used in genetic engineering, such as restriction enzymes and ligases. Real-life applications in medicine, agriculture, and biotechnology are explored to understand the impact of recombinant DNA on various fields.

  • Recombinant DNA II
    Graham Walker

    In Recombinant DNA II, students will delve deeper into the manipulation and analysis of DNA sequences. The module focuses on techniques like PCR, gel electrophoresis, and sequencing. Students will gain insights into the methodologies for amplifying and analyzing genetic material. Case studies highlight advancements in genetic research, forensic science, and personalized medicine, showcasing the broader implications of DNA technology.

  • Recombinant DNA III
    Graham Walker

    The third installment, Recombinant DNA III, examines advanced applications and ethical considerations in genetic engineering. Topics include CRISPR-Cas9 and gene therapy, focusing on their potential in treating genetic disorders. Students explore the societal implications and ethical debates surrounding gene editing. This module encourages critical thinking about the future of genetics and the responsibilities of scientists in the field.

  • Continuing from Recombinant DNA III, this module transitions to Immunology I, introducing the basics of the immune system. Students learn about innate and adaptive immunity, the role of white blood cells, and the body's response to pathogens. The module provides a foundation for understanding immune mechanisms and their relevance in disease prevention and vaccine development. Interactive discussions on current trends in immunology encourage further exploration.

  • Population Growth I
    Penny Chisholm

    Population Growth I focuses on the dynamics of population growth in various organisms. Topics include exponential and logistic growth models, factors influencing population size, and carrying capacity. By analyzing real-world data, students learn to apply mathematical models to predict population trends. The module emphasizes the ecological implications of population growth and challenges in managing resources for sustainable development.

  • Population Growth II
    Penny Chisholm

    Building on the previous module, Population Growth II delves into complex interactions affecting populations. Students study predator-prey dynamics, population genetics, and the effects of environmental changes. By exploring case studies, they gain insights into conservation biology, endangered species, and the impact of human activities on ecosystems. The module fosters critical thinking about biodiversity and strategies for mitigating adverse effects.

  • The final module, Population Genetics and Evolution, integrates evolutionary theories with genetic principles. Students explore natural selection, genetic drift, and gene flow in shaping populations. The module covers speciation, adaptation, and the role of genetic diversity in evolution. Through simulations and exercises, students apply theoretical concepts to understand evolutionary processes, fostering an appreciation for the complexity and interconnectedness of life.

  • Molecular Evolution
    Martin Polz

    Molecular Evolution explores the processes that drive the changes in genetic sequences over time. This module covers key concepts such as:

    • The mechanisms of mutation and selection
    • Phylogenetics and the tree of life
    • The role of genetic drift and gene flow
    • Applications of molecular evolution in understanding biodiversity

    Students will engage in discussions on how molecular evolution informs our understanding of species adaptation and the historical context of life on Earth.

  • Communities I
    Penny Chisholm

    Communities I introduces the interaction between various species within ecological communities. The module delves into:

    • The principles of community structure and diversity
    • Trophic levels and energy flow in ecosystems
    • Species interactions such as predation, competition, and mutualism
    • The impact of human activities on community dynamics

    Through case studies and fieldwork, students will gain insights into the complexity of ecological relationships and the importance of preserving biodiversity.

  • Communities II
    Penny Chisholm

    Communities II builds upon the concepts from Communities I, further investigating complex interactions within ecosystems. Topics include:

    • Succession and ecosystem development
    • Landscape ecology and habitat fragmentation
    • Species diversity and its ecological significance
    • Conservation strategies for sustaining community health

    The module involves field studies and data analysis to assess community health and explore strategies for ecosystem restoration.

  • Molecular Biology 1
    Eric Lander

    Molecular Biology 1 covers the foundational aspects of molecular biology, emphasizing critical concepts such as:

    • The structure and function of nucleic acids
    • The processes of DNA replication, transcription, and translation
    • Gene regulation and expression mechanisms
    • Protein structure and function

    This module integrates laboratory techniques to explore molecular biology applications in research and biotechnology, providing hands-on experience in genetic analysis.

  • Immunology II
    Graham Walker

    Immunology II delves deeper into the immune system's functions and responses to pathogens. Key topics include:

    • The role of immune cells in pathogen recognition and response
    • Mechanisms of immune memory and vaccination
    • Immune system disorders and autoimmune diseases
    • The interplay between the immune system and microbiota

    Students will engage in discussions on current research in immunology and its implications for understanding health and disease.